A drug initially designed to treat diabetes may be a breakthrough treatment for Parkinson's disease. After decades of disappointment, could MSDC-0160 be the drug researchers have been searching for?
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Breaking research promises a much-needed Parkinson's breakthrough.
Parkinson's disease is a progressive condition that strikes the central nervous system.
Causing a range of motor symptoms, it develops gradually, starting with a subtle tremor.
Parkinson's affects an estimated 60,000 Americans and up to 10 million people worldwide.
Due to society's steadily increasing in lifespan, this figure is likely to increase over the coming years.
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Despite billions of dollars of research, there is still no cure for Parkinson's. A drug designed in the 70s - levodopa - is still in use, but its benefits are limited, and the side effects are troubling.
Currently, the only available drugs tackle the symptoms of Parkinson's; none make a dent on the processes that underpin the disease's progression.
Against this somber backdrop, any news of a potential breakthrough drug is likely to turn heads.
Research, published today in the journal Science Translational Medicine, provides such a glimmer of light. A drug, initially designed to treat diabetes, appears to tackle the underlying causes of Parkinson's. If this turns out to be the case, it will be the first of its kind and has the potential to change millions of lives.
MSDC-0160, diabetes, and Parkinson'sInvestigators from the Van Andel Research Institute's Center for Neurodegenerative Science in Great Rapids, MI, believe their recent findings show that MSDC-0160 could be the breakthrough medical science has been waiting for.
"We hope this will be a watershed moment for millions of people living with Parkinson's disease. All of our research in Parkinson's models suggests this drug could potentially slow the disease's progression in people as well."
Dr. Patrik Brundin, senior author
MSDC-0160 was designed by Kalamazoo, a Metabolic Solutions Development Company. As an insulin sensitizer, it was created to treat type 2 diabetes. The company focuses on looking for drugs that might be repurposed to treat conditions other than the ones they were designed for.
This drug has already been proven safe in humans, and its manufacturing process is already established; because of this, the path through clinical trials and into widespread use is shorter and simpler to navigate. Recent trials in a mouse model of Parkinson's have provided positive results, and trials in humans are now set to begin next year.
Tom Isaacs, co-founder of The Cure Parkinson's Trust, says:
"Our scientific team has evaluated more than 120 potential treatments for Parkinson's disease, and MSDC-0160 offers the genuine prospect of being a breakthrough that could make a significant and permanent impact on people's lives in the near future. We are working tirelessly to move this drug into human trials as quickly as possible in our pursuit of a cure."
tao mat troi spirulina
tao spirulina tu nhien dang bot
Breaking research promises a much-needed Parkinson's breakthrough.
Parkinson's disease is a progressive condition that strikes the central nervous system.
Causing a range of motor symptoms, it develops gradually, starting with a subtle tremor.
Parkinson's affects an estimated 60,000 Americans and up to 10 million people worldwide.
Due to society's steadily increasing in lifespan, this figure is likely to increase over the coming years.
co nen uong tao mat troi
Despite billions of dollars of research, there is still no cure for Parkinson's. A drug designed in the 70s - levodopa - is still in use, but its benefits are limited, and the side effects are troubling.
Currently, the only available drugs tackle the symptoms of Parkinson's; none make a dent on the processes that underpin the disease's progression.
Against this somber backdrop, any news of a potential breakthrough drug is likely to turn heads.
Research, published today in the journal Science Translational Medicine, provides such a glimmer of light. A drug, initially designed to treat diabetes, appears to tackle the underlying causes of Parkinson's. If this turns out to be the case, it will be the first of its kind and has the potential to change millions of lives.
MSDC-0160, diabetes, and Parkinson'sInvestigators from the Van Andel Research Institute's Center for Neurodegenerative Science in Great Rapids, MI, believe their recent findings show that MSDC-0160 could be the breakthrough medical science has been waiting for.
"We hope this will be a watershed moment for millions of people living with Parkinson's disease. All of our research in Parkinson's models suggests this drug could potentially slow the disease's progression in people as well."
Dr. Patrik Brundin, senior author
MSDC-0160 was designed by Kalamazoo, a Metabolic Solutions Development Company. As an insulin sensitizer, it was created to treat type 2 diabetes. The company focuses on looking for drugs that might be repurposed to treat conditions other than the ones they were designed for.
This drug has already been proven safe in humans, and its manufacturing process is already established; because of this, the path through clinical trials and into widespread use is shorter and simpler to navigate. Recent trials in a mouse model of Parkinson's have provided positive results, and trials in humans are now set to begin next year.
Tom Isaacs, co-founder of The Cure Parkinson's Trust, says:
"Our scientific team has evaluated more than 120 potential treatments for Parkinson's disease, and MSDC-0160 offers the genuine prospect of being a breakthrough that could make a significant and permanent impact on people's lives in the near future. We are working tirelessly to move this drug into human trials as quickly as possible in our pursuit of a cure."
tao mat troi spirulina